EGF RECEPTOR-TARGETED SYNTHETIC DOUBLE-STRANDED RNA ELIMINATES GLIOBLASTOMA, BREAST CANCER, AND ADENOCARCINOMA TUMORS IN MICE.

EGF receptor-targeted synthetic double-stranded RNA eliminates glioblastoma, breast cancer, and adenocarcinoma tumors in mice.

BACKGROUND: Glioblastoma multiforme (GBM) is the most lethal form of brain cancer.With the available treatments, survival does not exceed 12-14 mo from the time of diagnosis.We describe a novel strategy to selectively induce the death of glioblastoma cells and other cancer cells that over-express the EGF receptor.Using a non-viral delivery vector t

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Is resilience a protective factor against the effects of the COVID-19 pandemic on mental health? Results from a national multicentric study

The COVID-19 pandemic is impacting on the mental health of the general population and its consequences will be long lasting.As already noted in previous epidemics, different factors can moderate the detrimental impact of a traumatogenic event on mental health.In particular, it has been found that people using problem-solving coping strategies, with

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